Smarcc2基因
WebJan 15, 2024 · Human SMARCC2 full-length ORF ( AAH13045, 1 a.a. - 1130 a.a.) recombinant protein with GST-tag at N-terminal. 基因名称 : SMARCC2. 基因别名 : BAF170 CRACC2 Rsc8. 基因描述 : SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2. WebNov 23, 2024 · Switch/sucrose-nonfermenting (SWI/SNF) complexes play a key role in chromatin remodeling. Recent studies have found that SMARCC2, as the core subunit of the fundamental module of the complex ...
Smarcc2基因
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WebMar 21, 2024 · SMARCD2 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily D, Member 2) is a Protein Coding gene. Diseases associated with …
WebDec 8, 2024 · SMARCC2. -related neurodevelopmental disorder through exome analysis and reanalysis in two patients. Dong Li, Helen Downes, Cuiping Hou, Hakon Hakonarson, … WebJan 8, 2024 · SMARCC2. SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2. Gene ID: 6601, updated on 8-Jan-2024. Gene type: …
Websmarcc2突变很罕见，但可见于微卫星不稳定的胃癌和结直肠癌 。skarcc2外显子8的重复序列是移码突变的热点，分别存在于胃癌（9%）和结直肠癌（15%）中。该突变产生终止密 … WebNov 23, 2024 · SMARCC2 knockout promoted the proliferation of glioblastoma cells, while its overexpression showed the opposite effect. Mechanistically, SMARCC2 negatively regulates transcription by dynamically regulating the chromatin structure and closing the promoter region of the target gene DKK1, which can be bound by the transcription factor …
WebJan 3, 2024 · SMARCC2 (BAF170) is one of the invariable core subunits of the ATP-dependent chromatin remodeling BAF (BRG1-associated factor) complex and plays a crucial role in embryogenesis and corticogenesis. Pathogenic variants in genes encoding other components of the BAF complex have been associated with intellectual disability …
The protein encoded by this gene is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and contains a predicted leucine zipper motif typical of many transcription factors. Two transcript variants encoding different isofor… high school key biscayneWebSMARCC2 expression was knocked down in glioma cells using small interfering RNA (si) and overexpressed by infection with adenovirus vectors carrying SMARCC2 cDNA. Wound healing and Transwell assays were performed to assess cell migration and invasion, respectively. Subsequently, immunofluorescence and western blotting were performed to … high school kenyaWeb质粒载体网zlzt.com专业提供SMARCC2人源、小鼠、大鼠基因cDNA克隆质粒,产品编号为zl-042329,为科研单位及院所提供的质粒载体展示及购买平台,保藏了大量质粒载体,致力于完美质粒众筹,质粒合成,质粒构建,质粒提取,质粒保藏! high school kevin hartWebsmarcc2 作用功能 編輯 該基因編碼的蛋白是SWI/SNF蛋白家族的成員，其成員顯示螺旋酶和ATP酶的活性，並被認為通過改變這些基因周圍的染色質結構來調節某些基因的轉錄。 how many children does storm huntley havehttp://www.biofeng.com/gene/renyuan/SMARCC2.html how many children does swizz beatz haveWebNov 30, 2024 · Clinical Significance. A change in this gene was identified in a UDN participant and other patients with similar symptoms ( Machol et al. 2024 ). Gene … high school key club meaningWeb基因/基因ID: ARID1A(8289) 表达特异性: ... ACTL6A/BAF53, SMARCC1/BAF155, SMARCC2/BAF170, and SMARCB1/SNF5/BAF47. Other subunits specific to each of the complexes may also be present permitting several possible combinations developmentally and tissue specific. Component of the BAF (SWI/SNF-A) complex, which includes at least … high school keyboarding class