Fgfr2 antibody
WebOct 1, 2014 · In contrast, 7 commercially available anti-FGFR2 antibodies showed cross-reactivity with other FGF receptors. In an assay using cells with inducible FGFR2 gene expression, FPT mAb also was more sensitive for detection of FGFR2b than any of the commercially available antibodies. Furthermore, FPT mAb was able to detect FGFR2b … WebThese antibodies target FGFR1 in Human, Rat, Mouse, Non-human primate and Guinea Pig samples. Our FGFR1 polyclonal, monoclonal and recombinant monoclonal antibodies are developed in Rabbit, Mouse and Goat. Find the FGFR1 antibody that fits your needs. Choose from 1 of 64 FGFR1 antibodies, which have been validated in experiments with …
Fgfr2 antibody
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WebSep 9, 2024 · Background Fibroblast growth factor receptor (FGFR) 2 is overexpressed in several tumor types, including triple-negative breast cancer and gastric cancer, both of which have a high unmet medical need. Aprutumab ixadotin (BAY 1187982) is the first antibody–drug conjugate (ADC) to target FGFR2 and the first to use a novel auristatin … WebHuman FGFR2 (IIIb) Antibody Summary. Reacts with multiple isoforms of human FGF R2 although it shows a marked preference for human FGF R2 (IIIb) isoforms in some assays …
WebThese antibodies target FGF2 in Human, Mouse, Rat, Guinea Pig and Marsupial samples. Our FGF2 polyclonal, monoclonal, recombinant monoclonal and recombinant polyclonal … WebHuman FGFR2 Antibody Summary. Detects alpha isoforms (3 Ig-like domains) and beta isoforms (2 Ig-like domains) of human FGF R2 in direct ELISAs and Western blots. In …
WebFGFR2 Antibody (98739) [PE] Summary. Immunogen. S. frugiperda insect ovarian cell line Sf 21-derived recombinant human FGF R2 isoforms and mouse myeloma cell line NS0 … WebThe final dilution of the rabbit antihuman FGFR2 antibody (ab10648; Abcam) was 1:500, mouse antihuman HER2 antibody (ab79205; Abcam) was 1:500, and that of the rabbit antihuman c-MET antibody (ab39075; Abcam) was 1:200. Goat antirabbit immunoglobulin G (Beijing Zhongshan Golden Bridge Biotechnology Co., Ltd. Beijing, People’s Republic …
WebOct 1, 2024 · Thus, FGFR2 is regarded as an attractive tumor antigen for targeted alpha therapy. This study reports the evaluation of an FGFR2-targeted thorium-227 conjugate (FGFR2-TTC, BAY 2304058) comprising an anti-FGFR2 antibody, a chelator moiety covalently conjugated to the antibody, and the alpha particle-emitting radionuclide …
WebTo confirm specificity of the staining, additional IHC with a mouse anti-FGFR2 antibody (Sc-6930, Santa Cruz, Dallas, TX, USA) was performed in randomly selected samples. Issues caused by intra- and interlaboratory variability of immunohistochemical stain have been minimized by involving one technician who would conduct all procedures in one ... oreo paragraph templateWebChinese Hamster Ovary cell line, CHO-derived human FGFR2 alpha Arg22-Glu377 Accession # P21802.1 . Formulation. Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide. Label. Alexa Fluor 700 (Excitation= 675-700 nm, Emission= 723 nm) ... Human FGFR2 alpha Antibody. how to use an inkle loomWebApr 12, 2024 · FGFR2 fusions are determined by genomic rearrangements of the FGFR2 gene located on chromosome 10. FGFR2 fusions have been reported in up to 15% of iCCA, occur mostly in fluke-negative iCCA and are usually mutually exclusive with IDH1 mutations [10]. The FGFR2 can be involved in rearrangements with different genes. how to use an input maskWebSep 29, 2010 · C, FGFR2 cell surface expression by flow cytometry. The cells were incubated with 100 μL of primary FGFR2 antibodies (5 μg/mL) for 1 h, followed by incubation with 1:100 phycoerythrin (PE)-conjugated secondary antibodies (Jackson ImmunoResearch) for 30 min. Analysis of stained cells was performed on a FC500 flow … oreo paint schemeWebCreative Biolabs offers high-quality Mouse Anti-FGFR2 Monoclonal Antibody, Unconjugated to boost neuroscience research. how to use an input mask to prevent bad dataWebOct 31, 2016 · It consists of a fully human FGFR2 monoclonal antibody (mAb BAY 1179470), which binds to the FGFR2 isoforms FGFR2-IIIb and FGFR2-IIIc, conjugated through a noncleavable linker to a novel derivative of the microtubule-disrupting cytotoxic drug auristatin (FGFR2-ADC). oreo oval shaped barsWebFGFR2 Antibodies. (Fibroblast Growth Factor Receptor 2 (FGFR2)) The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. oreo paragraph writing